Chia-Hua Kuo

Area of Specialization

• Human Performance and Sports Nutrition
• Human Metabolism and Aging

Academic Appointments

Distinguished Professor (present)
Institute of Sports Sciences
University of Taipei, Taipei, Taiwan

Chair Professor (2023-present)
Soochow University

Education

Ph.D. (Interdisciplinary: Exercise Physiology, Biochemistry and Molecular Biology) University of Texas at Austin, 1994-1997

M.A. (Kinesiology) University of Texas at Austin, 1991-1994

B.A. Fu Jen University, 1984-1988

Selected Publications

1. Dewi L, Liao YC, Jean WH, Huang LC, Nicholls A. Lai L, Huang CY, Chang PC, Chen LK, Kuo CH. 2024. Cordyceps accelerates stem cell recruitment to human skeletal muscle after exercise. Food Funct. Accepted (Journal front cover).
2. Dewi L, Lin YC, Nicholls A, Condello G, Huang CY, Kuo CH. Pax7+ satellite cells in human skeletal muscle after exercise. Sports Med. 2023 Feb;53(2):457-480.
3. Lin KH, Ramesh S, Agarwal S, Kuo WW, Kuo CH, Chen MY, Lin YM, Ho TJ, Huang PC, Huang CY. Fisetin attenuates doxorubicin-induced cardiotoxicity by inhibiting the insulin-like growth factor II receptor apoptotic pathway through estrogen receptor-α/-β activation. Phytother Res. 2023
4. Wei CC, Condello G, Yang AL, Yu SH, Liao YH, Chen CY, Hsu CC, Huang CY, Kuo CH. Defecation enhances cerebral perfusion and delays fatigue in elite triathletes. J Int Soc Sports Nutr. 2023 Dec;20(1):2206380.
5. Hsieh CC, Chang CY, Yar Lee TX, Wu J, Saovieng S, Hsieh YW, Zhu M, Huang CY, Kuo CH. Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1. J Ginseng Res. 2023 Mar;47(2):210-217.
6. Jean WH, Hsieh YW, Lai LF, Dewi L, Liao YC, Ye M, Yu SH, Kao CL, Huang CY, Kuo CH. Senolytic effect of high intensity interval exercise on human skeletal muscle. Aging (Albany NY). 2023 Feb 8;15(3):765-776.
7. Khemtong C, Tessitore A, Jaime SJ, Gobbi G, Jensen J, Yang AL, Kuo CH, Condello G. Branched-Chain Amino Acids Supplementation Does Not Accelerate Recovery after a Change of Direction Sprinting Exercise Protocol. Nutrients. 2022 Oct 16;14(20):4331.
8. Lu SY, Hong WZ, Tsai BC, Chang YC, Kuo CH, Mhone TG, Chen RJ, Kuo WW, Huang CY. Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the IGF1R-PI3K-AKT survival pathway. J Hypertens. 2022 Dec 1;40(12):2502-2512.
9. Su SH, Sundhar N, Kuo WW, Lai SC, Kuo CH, Ho TJ, Lin PY, Lin SZ, Shih CY, Lin YJ, Huang CY. Artemisia argyi extract induces apoptosis in human gemcitabine-resistant lung cancer cells via the PI3K/MAPK signaling pathway. J Ethnopharmacol. 2022 Dec 5;299:115658.
10. Chen JK, Kuo CH, Kuo WW, Day CH, Wang TF, Ho TJ, Lin PY, Lin SZ, Shih TC, Shih CY, Huang CY, Lu CY. Artemisia argyi extract ameliorates IL-17A-induced inflammatory response by regulation of NF-κB and Nrf2 expression in HIG-82 synoviocytes. Environ Toxicol. 2022 Nov;37(11):2793-2803.
11. Ho TJ, Goswami D, Kuo WW, Kuo CH, Yen SC, Lin PY, Lin SZ, Hsieh DJ, Shibu MA, Huang CY. Artemisia argyi exhibits anti-aging effects through decreasing the senescence in aging stem cells. Aging (Albany NY). 2022 Aug 9;14(15):6187-6201.
12. Mhone TG, Chen MC, Kuo CH, Shih TC, Yeh CM, Wang TF, Chen RJ, Chang YC, Kuo WW, Huang CY. Daidzein Synergizes with Gefitinib to Induce ROS/JNK/c-Jun Activation and Inhibit EGFR-STAT/AKT/ERK Pathways to enhance Lung Adenocarcinoma cells chemosensitivity. Int J Biol Sci. 2022 May 16;18(9):3636-3652.
13. Wu LK, Agarwal S, Kuo CH, Kung YL, Day CH, Lin PY, Lin SZ, Hsieh DJ, Huang CY, Chiang CY. Artemisia Leaf Extract protects against neuron toxicity by TRPML1 activation and promoting autophagy/mitophagy clearance in both in vitro and in vivo models of MPP+/MPTP-induced Parkinson's disease. Phytomedicine. 2022 Sep;104:154250.
14. Ju DT, Tsai BC, Sitorus MA, Kuo WW, Kuo CH, Chen TS, Hsieh DJ, Ho TJ, Huang CY, Wang CH. Curcumin-Pretreated Adipose-Derived Stem Cells Enhance the Neuroprotective Ability to Repair Rheumatoid Arthritis-Induced Damage in the Rat Brain. Am J Chin Med. 2022;50(5):1299-1314.
15. Chottidao M, Kuo CH, Tsai SC, Hwang IS, Lin JJ, Tsai YS. A Comparison of Plyometric and Jump Rope Training Programs for Improving Punching Performance in Junior Amateur Boxers. Front Bioeng Biotechnol. 2022 May 24;10:878527.
16. Lin CY, Lin YC, Paul CR, Hsieh DJ, Day CH, Chen RJ, Kuo CH, Ho TJ, Shibu MA, Lai CH, Shih TC, Kuo WW, Huang CY. Isoliquiritigenin ameliorates advanced glycation end-products toxicity on renal proximal tubular epithelial cells. Environ Toxicol. 2022 Aug;37(8):2096-2102.
17. Zhu M, Lee TXY, Hsieh YW, Lai LF, Condello G, Donnelly CJ, Smith M, Hamzah SH, Lim BH, Huang CY, Chi NF, Kuo CH. Vascular function in the aging human brain during muscle exertion. Aging (Albany NY). 2022 May 2;14(9):3910-3920.
18. Ju DT, Van Thao D, Lu CY, Ali A, Shibu MA, Chen RJ, Day CH, Shih TC, Tsai CY, Kuo CH, Huang CY. Protective effects of CHIP overexpression and Wharton's jelly mesenchymal-derived stem cell treatment against streptozotocin-induced neurotoxicity in rats. Environ Toxicol. 2022 Aug;37(8):1979-1987.
19. Lin HC, Paul CR, Kuo CH, Chang YH, Chen WS, Ho TJ, Day CH, Velmurugan BK, Tsai Y, Huang CY. Glycyrrhiza uralensis root extract ameliorates high glucose- induced renal proximal tubular fibrosis by attenuating tubular epithelial- myofibroblast transdifferentiation by targeting TGF-β1/Smad/Stat3 pathway. J Food Biochem. 2022 May;46(5):e14041.
20. Ho TJ, Chi-Kang Tsai B, Kuo CH, Luk HN, Day CH, Jine-Yuan Hsieh D, Chen RJ, Kuo WW, Kumar VB, Yao CH, Huang CY. Arecoline induces cardiotoxicity by upregulating and activating cardiac hypertrophy-related pathways in Sprague- Dawley rats. Chem Biol Interact. 2022 Feb 25;354:109810.
21. Lu CY, Day CH, Kuo CH, Wang TF, Ho TJ, Lai PF, Chen RJ, Yao CH, Viswanadha VP, Kuo WW, Huang CY. Calycosin alleviates H2 O2 -induced astrocyte injury by restricting oxidative stress through the Akt/Nrf2/HO-1 signaling pathway. Environ Toxicol. 2022 Apr;37(4):858-867.
22. Lin KH, Ali A, Kuo CH, Yang PC, Kumar VB, Padma VV, Lo JF, Huang CY, Kuo WW. Carboxyl terminus of HSP70-interacting protein attenuates advanced glycation end products-induced cardiac injuries by promoting NFκB proteasomal degradation. J Cell Physiol. 2022 Mar;237(3):1888-1901.