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A walk through the new ISC 2

  • In the dyad suite in ISC2
    In the dyad suite in ISC2  Constance Pilkington, chair of the psychology department, takes notes from the observation room in the dyadic interaction suite. Dyads—pairs of people—can be studied either through the two-way mirror or by video. The observation room controls four encounter rooms. Photo by Stephen Salpukas.  
  • Room for the confocal
    Room for the confocal  Dan Zabransky ’09 uses the confocal microscope in Matthew Wawersik’s lab. “Having this home for our own little confocal is just a phenomenal thing. The advantage is that it allows you to take thin sections of tissues—less than a micrometer—optically,” Wawersik said. Photo by Stephen Salpukas.  
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You have to keep reminding yourself that you’re inside what used to be Rogers Hall. The venerable chemistry building has been gutted and transformed into a state-of-the-art working space now known as Phase 2 of the Integrated Science Center. The chemists aren’t around, either; they moved to new quarters in the first phase of the Integrated Science Center last summer.Paul Kieffaber, assistant professor of psychology, shows off one of the Faraday chambers in the department’s EEG lab. “We have two different booths where we can run,“ Kieffaber said. “We just pop them in a chair, put a cap on their heads and start recording their brain waves.” The Faraday chambers provide isolation from “noise” coming from lights and electrical sources.

The lion’s share of the psychology department is on the first floor of ISC 2. The second floor is occupied by biologists, whose new department headquarters is in the adjoining ISC 1. ISC 1 is new construction that opened last summer.

In late April, there was still some unpacking and setting up going on, but actual science was going on in most of the labs. The biologists had moved over from Millington Hall, as had most of the psychologists. The departments aren’t 100 percent consolidated, though; there are a few psych people left in the Bell Building and some biologists remain in Millington. In the ISC 2, much of the talk in both departments had to do with how much better things were.

“This is a nice, big open space,” psychologist Peter Vishton said, looking around his new facility. Vishton, who moved his lab over from cramped quarters in the basement of the Bell Building, works on studies involving visually controlled actions, especially in infants. “The parents will be more comfortable; that will make the babies more comfortable—and that will give us better data.”
“This thing was my answer to lack of a window in my lab,” Matt Wawersik says, gesturing to the large monitor on the wall. “This is a great teaching tool.” Wawersik studies the genetics of stem cells in fruit flies, inducing mutation to identify the cause of change in individual stem cells. His work has implications for human health issues ranging from fertility to cancer: “There’s a cancer stem cell hypothesis that basically says that the hardest to treat cancers actually have cancer stem cells at the root of them—stem cells that have transformed into a cancer cell.”
Joseph Galano, meeting with a graduate student (“For the first time, we have a window!”), said he usually works with seven or eight undergraduate students, researching prevention of child abuse and neglect, often in partnership with the group Prevent Child Abuse Virginia.

“I’m very fortunate here at William and Mary to have wonderful undergraduate students,” Galano said. “We used to work in a closet; now we have a wonderful research space.”

Constance Pilkington, psychology chair, paused outside the department conference room where a group was assembling to hear a senior’s honors project presentation.

“Our new seminar rooms provide us with a lot more space to host invited speakers and to have research meetings,” Pilkington said.

The ISC 2 benefits go beyond better, more pleasant and more convenient work spaces. Like the adjoining first phase of the Integrated Science Center, the ISC 2 was built with the needs of the scientists in mind. The psychologists, for example, now have a dedicated computer-driven research lab, no longer having to make do with a patched-together collection of machines.

“Computers are our microscopes and our test tubes,” Pilkington said. “I know everyone uses computers, but we use computers to collect so much of our data. Using a computer, we can get reaction time and that tells us all sorts of things about what goes on in the brain. We collect physiological data and that tells us about your emotional state.”

The psych department’s new computer infrastructure even extends to a pair of Faraday chambers, electrically shielded booths that allow researchers in the EEG lab to get better data when they monitor brain activity in human subjects.
Peter Vishton works with a group of students in one of the new computer facilities in the ISC 2. One of the 16 psychology laboratories in the Integrated Science Center complex is a dedicated computer lab. Department Chair Constance Pilkington says, “I know everybody uses computers, but for psychologists, they really are our test tubes. We really wouldn’t be able to collect the data that we’re collecting without them.”
“Right now these fluorescents are flickering at 60 hertz—that’s 60 times a second,” Assistant Professor Paul Kieffaber explained. “All the outlets in the walls, they are pulsating with alternating current. All of this creates electrical noise. The sensors that we use to record brain activity are so sensitive that they pick up on all this kind of environmental noise; in fact that noise is much louder than the kind of activity that we’re able to record at the surface of the scalp.”

Kieffaber said until the Faraday chambers were installed, researchers used software to filter out the electrical noise. “It’s easy. And,” he said, “it distorts your data.” Pilkington said that the shielded booths are almost never seen in a school the size of William & Mary, but will be valuable for a large part of the psychology faculty.

“The cool thing about this is we’ve got cognitive psychologists, clinical psychologists, social psychologists, pretty much the whole spectrum of psychology can come in here and do brain recording,” she said.Karl Mendoza, a master’s student in biology, works on neural anatomy in the lab of John Griffin, Class of 2012 Associate Professor of Biology and director of the neuroscience program. The two are working to perfect a gold nanoprobe staining system designed by Mendoza. Adapting a probe used in cancer treatment, their aim is to develop a tool to label specific individual neurons. “The goal is that we’ll be able to go back and record from those cells, so we’ll be able to trace where they connect to and we’ll know their physiology,” Griffin said.

Like the EEG lab, Pilkington said the department’s new dyadic interaction lab will see wide use. A suite of four interaction rooms are connected to an observation room by video as well as two-way mirrors.

“Because we have these four rooms in the suite, we can have people interacting together, then break them out into separate rooms,” Pilkington said. “We can watch everything that’s going on from the central control room.”

On the second floor, a similar metamorphosis was underway in biology labs.

“It’s bright, it’s open. It’s a great place to be. This is really a great change,” said Matt Wawersik, a biologist who works with stem cells in fruit flies. “We have our own miJoseph Galano, associate professor, meets with Carla Correia, first-year Psy.D. student. Galano conducts research on the prevention of child abuse and neglect, often involving students in his work. Correia is the graduate student representative on the Prevention and Promotion Advisory Council to the State Department of Mental Health.croscope room. Before, we just had this makeshift shell that was really a box we went into. We have the rooms across the way that are colloquium space that we can meet for teaching and for lunches or lab meetings.”

Opening of the Integrated Science Center Phase 2 is the latest milestone in the development of a science precinct at William & Mary. The first phase of the ISC opened for business in summer of 2008. Taken together, ISC 1 and 2 provide a total of 70 teaching and research laboratories (plus faculty offices and support facilities) for the departments of chemistry, biology and psychology. Plans are being developed for the third phase of the Integrated Science Center.