Core faculty research interests include: Nondestructive Evaluation, Robotics and Medical Imaging; Nanotechnology and Thin Films, Surface Science, Electronic and Magnetic Materials Science; Laser Spectroscopy; Physical and Chemical Properties and Characterization of Polymers; Solid State Nuclear Magnetic Resonance; Neurophysiology and Cell Biology; Computational Neuroscience; Biophysical Chemistry & Structural Biology; Plasma Modeling and Fusion Science; Geospatial Analysis.

Applied Science research takes place both on and off campus. Facilities include the Intergrated Science Center (ISC 3), the Beowulf-like SciClone parallel computing system, the solid state NMR spectroscopy laboratory, the NASA-Langley Research Center (NASA-LaRC) and The Thomas Jefferson National Accelerator Facility (Jefferson Lab).