Jessica Joyce


Stamps 1693 Scholar

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Broadlands, VA (Briar Woods High School, Academy of Science)

Why W&M

The two things I knew I needed in a college were the opportunity to conduct original, independent research as an undergraduate and the ability to develop a close relationship with my professors. Knowing this, William & Mary was on my shortlist of colleges to attend. After multiple visits to the school, I was convinced it was the place for me. Not only does William & Mary have the research opportunities and professor-student involvement I wanted, but it offers things that cannot be described in a college brochure. The students I met at William & Mary during the interview weekend impressed me with their research projects and achievements, but I was even more impressed by their passion and appreciation for the world that existed outside of their particular talents. Each person I met at William & Mary was committed to serving others, ultimately showing me that William & Mary was the ideal place to pursue my undergraduate studies.


Biology major and Chemistry minor

W&M Activities and Research

  • Dr. Lisa Landino's lab
    • My work in Dr. Landino’s lab investigates oxidative damage to proteins exhibited in Alzheimer’s disease. My current focus is the glycolytic enzyme lactate dehydrogenase (LDH). LDH contains reduced cysteines and has been identified as a target for cysteine oxidation in proteomics studies, and has a basic pI value that suggests that it may interact with acidic tubulin. To date, my research has shown that rabbit muscle LDH exhibits oxidized cysteines and inhibited activity when exposed to low micromolar concentrations of HOCl. DTNB did not inhibit LDH activity, but smaller cysteine reagents including iodoacetamide and N-ethylmaleimide did inhibit activity, suggesting that essential cysteines are sterically hindered. Preincubation of LDH with the cofactor NAD+ protected it from cysteine oxidation by HOCl and from inhibition. Further research will determine structural implications of LDH oxidation and investigate the effect of LDH oxidation on the transcriptional regulation activity of LDH.
  • Students for Effective Policy (STEP)
    • Student organization dedicated to identifying pragmatic, bipartisan policy solutions to problems facing the policymaking community and informing students about current issues in the policymaking community
  • Sharpe Community Scholar
    • Researched civic engagement in higher education and volunteered at a local assisted senior living facility
  • Howard Hughes Medical Institute Freshman Research Program
  • Program on International Peace and Security (PIPS)
    • An undergraduate think tank designed to connect the academic and foreign policy communities
    • As an intern, I participated in writing a policy proposal with a PIPS fellow, focusing on the need for federal regulation for cryptocurrency exchanges
  • Piano instruction with Professor Eric Lyttle
  • Professor Shantá Hinton’s lab
    • Conducting research on the role of the pseudophosphatase MK-STYX in the amyloid cascade. 
High School Activities
  • Secretary General of Model United Nations
  • Varsity lacrosse
  • Oboist in school band
  • Research collaboration with Hwa Chong Institution in Singapore
  • Independent research on Alzheimer’s disease
  • Competitive dance
  • Phi Beta Kappa
  • Research published in Journal of Experimental Secondary Science
  • Briar Woods High School Salutatorian
  • National Merit Scholar
  • National AP Scholar with Honor
  • Intel International Science and Engineering Fair Finalist
  • Howard Hughes Medical Institute Science Scholar
  • American Psychological Association Award
  • National Latin Exam Summa Cum Laude